Motif ID: NFY{A,B,C}.p2

Z-value: 3.263


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYAchr6_+_411488690.757.8e-04Click!
NFYCchr1_+_409302330.467.1e-02Click!
NFYBchr12_-_103055924-0.371.5e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_+_23175383 8.648 NM_005794
NM_182908
DHRS2

dehydrogenase/reductase (SDR family) member 2

chr17_+_73694992 4.663 NM_001010982
NM_001145526
AFMID

arylformamidase

chr17_-_73694669 4.527 NM_003258
TK1
thymidine kinase 1, soluble
chr17_+_70256518 3.952


chr8_+_11697588 3.899 NM_004462
FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr1_+_144149794 3.845 NM_006472
TXNIP
thioredoxin interacting protein
chr14_+_38714111 3.781 NM_002687
PNN
pinin, desmosome associated protein
chr20_+_47096280 3.615 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr20_+_47096189 3.578 NM_001316
CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr17_+_70256341 3.463 NM_004252
SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_+_70256389 3.422 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr2_+_74914742 3.407 HK2
hexokinase 2
chr17_+_70256397 3.392 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_77411733 3.376 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_+_70256370 3.364 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_77411803 3.316 NM_000918
P4HB
prolyl 4-hydroxylase, beta polypeptide
chr1_+_225194622 3.235 ADCK3
aarF domain containing kinase 3
chr17_-_77411695 3.202 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_-_77411659 3.197 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_-_77411707 3.138 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr1_+_110683586 2.968 RBM15
RNA binding motif protein 15
chr1_+_225194616 2.953 ADCK3
aarF domain containing kinase 3
chr1_+_110683580 2.945 RBM15
RNA binding motif protein 15
chr1_+_225194582 2.920 ADCK3
aarF domain containing kinase 3
chr1_+_225194560 2.877 NM_020247
ADCK3
aarF domain containing kinase 3
chr17_-_67628523 2.875 FLJ37644
hypothetical LOC400618
chr17_+_67628772 2.865 SOX9
SRY (sex determining region Y)-box 9
chr22_+_36384647 2.819 NM_020315
PDXP
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr8_+_11697680 2.819 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_+_11697616 2.784 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr8_+_11697706 2.778 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr1_+_110683467 2.767 NM_022768
RBM15
RNA binding motif protein 15
chr17_+_78070853 2.658 NM_004514
FOXK2
forkhead box K2
chr19_+_1220244 2.622 NM_001280
CIRBP
cold inducible RNA binding protein
chr17_-_77411607 2.598 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr7_+_149707338 2.592 NM_173680
ZNF775
zinc finger protein 775
chr6_-_166960649 2.545 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_26305456 2.539 HIST1H3D
histone cluster 1, H3d
chr14_+_23654307 2.513 NM_181357
DCAF11
DDB1 and CUL4 associated factor 11
chr8_+_126079900 2.512 NM_003129
SQLE
squalene epoxidase
chr8_+_11697929 2.498 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr1_+_51968191 2.490 OSBPL9
oxysterol binding protein-like 9
chr2_+_74539039 2.482 NM_012477
WBP1
WW domain binding protein 1
chr5_+_74668776 2.481 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr5_+_74668799 2.477 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr14_+_23008723 2.451 NM_001042635
NM_015514
NGDN

neuroguidin, EIF4E binding protein

chr20_-_45418818 2.431 NM_012408
NM_183047
NM_183048
ZMYND8


zinc finger, MYND-type containing 8


chr5_+_74668822 2.426 HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr16_-_11798507 2.380 ZC3H7A
zinc finger CCCH-type containing 7A
chr16_+_10387412 2.348 ATF7IP2
activating transcription factor 7 interacting protein 2
chr16_-_88410523 2.345 NM_000135
NM_001018112
FANCA

Fanconi anemia, complementation group A

chr5_+_74668748 2.295 NM_000859
NM_001130996
HMGCR

3-hydroxy-3-methylglutaryl-CoA reductase

chr6_+_31891293 2.264 HSPA1A
heat shock 70kDa protein 1A
chr2_+_86521939 2.248 KDM3A
lysine (K)-specific demethylase 3A
chr17_+_23670247 2.236 NM_014573
TMEM97
transmembrane protein 97
chr17_+_71772875 2.232 NM_182565
FAM100B
family with sequence similarity 100, member B
chr1_+_51968046 2.227 NM_148904
NM_148905
NM_148907
OSBPL9


oxysterol binding protein-like 9


chr2_-_73313823 2.217 NM_032319
C2orf7
chromosome 2 open reading frame 7
chr1_+_51968096 2.198 OSBPL9
oxysterol binding protein-like 9
chr6_+_31891259 2.192 NM_005345
HSPA1A
heat shock 70kDa protein 1A
chr14_-_22458134 2.191 RBM23
RNA binding motif protein 23
chr6_-_166960496 2.180 RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr6_-_166960690 2.154 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr2_+_203207912 2.137 FAM117B
family with sequence similarity 117, member B
chr14_+_23008742 2.128 NGDN
neuroguidin, EIF4E binding protein
chr2_+_203208064 2.123 NM_173511
FAM117B
family with sequence similarity 117, member B
chr14_-_22458199 2.102 RBM23
RNA binding motif protein 23
chr14_-_22458220 2.069 NM_001077351
NM_001077352
NM_018107
RBM23


RNA binding motif protein 23


chr14_+_23654161 2.045 DCAF11
DDB1 and CUL4 associated factor 11
chr6_-_31890765 2.041 NM_005527
HSPA1L
heat shock 70kDa protein 1-like
chr2_+_85676347 2.040 NM_016494
RNF181
ring finger protein 181
chr6_+_24883133 2.010 NM_015895
GMNN
geminin, DNA replication inhibitor
chr16_+_88154638 2.005 RPL13
ribosomal protein L13
chr16_+_88154582 1.995 NM_000977
NM_033251
RPL13

ribosomal protein L13

chr2_+_86521999 1.980 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr19_-_6643953 1.976 C3
complement component 3
chr5_+_44844724 1.975 NM_016640
MRPS30
mitochondrial ribosomal protein S30
chr13_+_96672541 1.931 NM_144778
NM_207304
MBNL2

muscleblind-like 2 (Drosophila)

chr3_+_9414290 1.931 NM_001080517
SETD5
SET domain containing 5
chr16_+_88154562 1.925 RPL13
ribosomal protein L13
chr6_+_160103500 1.898 ACAT2
acetyl-CoA acetyltransferase 2
chr7_+_99974781 1.895 AGFG2
ArfGAP with FG repeats 2
chr7_+_99974720 1.895 NM_006076
AGFG2
ArfGAP with FG repeats 2
chr10_+_1085443 1.885 WDR37
WD repeat domain 37
chr16_+_8675904 1.865 NM_020686
ABAT
4-aminobutyrate aminotransferase
chr14_-_23653965 1.858 NRL
neural retina leucine zipper
chr6_+_31891509 1.844 HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr13_+_96672705 1.824 MBNL2
muscleblind-like 2 (Drosophila)
chr1_+_210525490 1.822 NM_006243
PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr3_-_9414122 1.791 LOC440944
hypothetical LOC440944
chr19_+_54160369 1.784 NM_000146
FTL
ferritin, light polypeptide
chr11_+_63710242 1.767 STIP1
stress-induced-phosphoprotein 1
chr18_+_75967902 1.753 NM_014913
ADNP2
ADNP homeobox 2
chr1_+_210525397 1.748 PPP2R5A
protein phosphatase 2, regulatory subunit B', alpha
chr17_+_44325127 1.732 NM_001002027
NM_005175
ATP5G1

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C1 (subunit 9)

chr19_+_54160399 1.710 FTL
ferritin, light polypeptide
chr17_+_71772982 1.704 FAM100B
family with sequence similarity 100, member B
chr14_+_23653848 1.698 DCAF11
DDB1 and CUL4 associated factor 11
chr11_+_63710206 1.692 STIP1
stress-induced-phosphoprotein 1
chr1_-_148080888 1.689 NM_001040874
NM_003516
HIST2H2AA4
HIST2H2AA3
histone cluster 2, H2aa4
histone cluster 2, H2aa3
chr11_+_34416997 1.689 NM_001752
CAT
catalase
chr2_+_26862416 1.684 CENPA
centromere protein A
chr19_+_4920123 1.668 NM_015015
KDM4B
lysine (K)-specific demethylase 4B
chr3_+_195336625 1.654 NM_005524
HES1
hairy and enhancer of split 1, (Drosophila)
chr6_+_37245860 1.636 NM_002648
PIM1
pim-1 oncogene
chr17_+_43480674 1.632 NM_003204
NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr10_+_62208094 1.630 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr19_-_45948211 1.595 C19orf54
chromosome 19 open reading frame 54
chr17_+_43480723 1.593 NFE2L1
nuclear factor (erythroid-derived 2)-like 1
chr16_-_10943716 1.582 NM_014015
DEXI
Dexi homolog (mouse)
chr17_+_54587882 1.573 PRR11
proline rich 11
chr1_+_167342149 1.567 ATP1B1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr4_+_166468266 1.551 NM_001017369
NM_006745
SC4MOL

sterol-C4-methyl oxidase-like

chr17_+_58981550 1.542 NM_005828
DCAF7
DDB1 and CUL4 associated factor 7
chr17_+_58981573 1.535 DCAF7
DDB1 and CUL4 associated factor 7
chr20_+_48781457 1.528 NM_032521
PARD6B
par-6 partitioning defective 6 homolog beta (C. elegans)
chr16_+_66676851 1.517 NM_004555
NM_173163
NM_173164
NM_173165
NFATC3



nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3



chr16_-_10943656 1.516 DEXI
Dexi homolog (mouse)
chr17_+_58981582 1.512 DCAF7
DDB1 and CUL4 associated factor 7
chr3_+_121296290 1.512


chr16_-_10943778 1.511 DEXI
Dexi homolog (mouse)
chr5_+_150380270 1.511 GPX3
glutathione peroxidase 3 (plasma)
chr16_+_66676833 1.504 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr10_+_62208256 1.502 CDK1
cyclin-dependent kinase 1
chr14_+_23653819 1.499 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr11_+_63710162 1.495 NM_006819
STIP1
stress-induced-phosphoprotein 1
chr16_+_55523526 1.493 HERPUD1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr9_+_4782833 1.490 NM_005772
RCL1
RNA terminal phosphate cyclase-like 1
chr9_+_91115924 1.488 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr22_+_48740143 1.480 NM_001001852
PIM3
pim-3 oncogene
chr10_+_104667991 1.477 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr19_+_54160468 1.474 FTL
ferritin, light polypeptide
chr11_-_47154955 1.470 NM_032389
ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr19_-_45948189 1.465 C19orf54
chromosome 19 open reading frame 54
chr9_+_73716347 1.464 C9orf85
chromosome 9 open reading frame 85
chr19_+_45948598 1.460 NM_004596
SNRPA
small nuclear ribonucleoprotein polypeptide A
chr1_+_27192719 1.453 NM_001013642
TRNP1
TMF1-regulated nuclear protein 1
chr5_+_150380325 1.453 GPX3
glutathione peroxidase 3 (plasma)
chr2_+_96845704 1.452 NM_017623
NM_199078
CNNM3

cyclin M3

chr14_+_23711044 1.451 NM_001048205
NM_005132
REC8

REC8 homolog (yeast)

chr2_-_3360467 1.435 NM_003310
TSSC1
tumor suppressing subtransferable candidate 1
chr17_+_67628749 1.428 NM_000346
SOX9
SRY (sex determining region Y)-box 9
chr17_+_78009895 1.428 NARF
nuclear prelamin A recognition factor
chr5_+_150380173 1.419 NM_002084
GPX3
glutathione peroxidase 3 (plasma)
chr17_+_71773026 1.412 FAM100B
family with sequence similarity 100, member B
chr3_+_195336631 1.411 HES1
hairy and enhancer of split 1, (Drosophila)
chr14_+_23653745 1.410 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr3_+_9414533 1.409 SETD5
SET domain containing 5
chr11_+_34417109 1.402 CAT
catalase
chr1_+_12002138 1.400 MIIP
migration and invasion inhibitory protein
chr20_+_41519947 1.395 SRSF6
serine/arginine-rich splicing factor 6
chr2_+_223433919 1.395 NM_004457
NM_203372
ACSL3

acyl-CoA synthetase long-chain family member 3

chr16_-_10943803 1.384 DEXI
Dexi homolog (mouse)
chr11_-_47154996 1.381 ARFGAP2
ADP-ribosylation factor GTPase activating protein 2
chr14_-_72430545 1.379 NM_012074
DPF3
D4, zinc and double PHD fingers, family 3
chr2_+_86800898 1.366 NM_022780
RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr9_-_73715927 1.359 NM_001025780
NM_016014
FAM108B1

family with sequence similarity 108, member B1

chr9_+_4782876 1.351 RCL1
RNA terminal phosphate cyclase-like 1
chr17_+_67628763 1.351 SOX9
SRY (sex determining region Y)-box 9
chr19_+_55398680 1.338 NM_001077186
NM_001145809
NM_024729
MYH14


myosin, heavy chain 14, non-muscle


chr11_+_550868 1.337 NM_001143993
RASSF7
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr20_+_41519882 1.335 NM_006275
SRSF6
serine/arginine-rich splicing factor 6
chr6_+_64339869 1.332 NM_003463
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr17_+_58981648 1.330 DCAF7
DDB1 and CUL4 associated factor 7
chr2_+_62786290 1.328 NM_001142616
NM_015252
EHBP1

EH domain binding protein 1

chr2_+_86800940 1.328 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr2_+_10101081 1.317 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr6_+_31903374 1.310 NM_005346
HSPA1A
HSPA1B
heat shock 70kDa protein 1A
heat shock 70kDa protein 1B
chr5_+_151131704 1.307 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr1_+_161027115 1.301 NM_016371
HSD17B7
hydroxysteroid (17-beta) dehydrogenase 7
chr20_+_36988368 1.296 NM_030919
FAM83D
family with sequence similarity 83, member D
chr7_+_127079466 1.295 SND1
staphylococcal nuclease and tudor domain containing 1
chr6_+_30796121 1.291 TUBB
tubulin, beta
chr9_+_73716189 1.288 NM_182505
C9orf85
chromosome 9 open reading frame 85
chr20_+_36988469 1.288 FAM83D
family with sequence similarity 83, member D
chr11_-_57236086 1.288 NM_153450
MED19
mediator complex subunit 19
chr6_+_26264531 1.287 HIST1H1E
histone cluster 1, H1e
chr11_+_43658718 1.286 NM_016142
HSD17B12
hydroxysteroid (17-beta) dehydrogenase 12
chr6_-_31938572 1.286 NM_000434
NEU1
sialidase 1 (lysosomal sialidase)
chr6_-_37333338 1.285 NM_145316
TMEM217
transmembrane protein 217
chr20_+_61967033 1.284 NM_003288
NM_199359
NM_199360
NM_199361
NM_199362
NM_199363
TPD52L2





tumor protein D52-like 2





chr6_+_26264537 1.284 NM_005321
HIST1H1E
histone cluster 1, H1e
chr2_+_86801081 1.282 RMND5A
required for meiotic nuclear division 5 homolog A (S. cerevisiae)
chr17_+_43374021 1.280 PNPO
pyridoxamine 5'-phosphate oxidase
chr2_+_8739563 1.277 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr5_+_151131676 1.273 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr7_+_882704 1.269 NM_015949
GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr1_+_12002098 1.268 NM_021933
MIIP
migration and invasion inhibitory protein
chr20_+_60246971 1.268 OSBPL2
oxysterol binding protein-like 2
chr1_+_205992004 1.264 NM_002389
NM_153826
NM_172350
NM_172351
NM_172352
NM_172353
NM_172359
NM_172361
CD46







CD46 molecule, complement regulatory protein







chr2_+_69995656 1.263 NM_002357
MXD1
MAX dimerization protein 1
chr20_+_60246972 1.262 NM_014835
NM_144498
OSBPL2

oxysterol binding protein-like 2

chr11_+_58103151 1.262 NM_001197051
NM_053023
ZFP91

zinc finger protein 91 homolog (mouse)

chr7_+_127079481 1.259 SND1
staphylococcal nuclease and tudor domain containing 1
chr5_+_151131707 1.258 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr20_+_60246982 1.255 OSBPL2
oxysterol binding protein-like 2
chr7_+_882766 1.252 GET4
golgi to ER traffic protein 4 homolog (S. cerevisiae)
chr19_+_63482118 1.250 NM_021089
ZNF8
zinc finger protein 8
chr10_+_38685299 1.243 HSD17B7P2
hydroxysteroid (17-beta) dehydrogenase 7 pseudogene 2
chr5_+_179058615 1.243 CANX
calnexin

Gene Ontology Analysis

Gene overrepresentation in process category:

enrichment   p-value GO term description
1.47 4.19e-19 GO:0044260 cellular macromolecule metabolic process
1.35 1.11e-18 GO:0044237 cellular metabolic process
1.31 1.16e-14 GO:0044238 primary metabolic process
1.28 1.42e-14 GO:0008152 metabolic process
1.64 2.37e-14 GO:0090304 nucleic acid metabolic process
2.33 7.32e-14 GO:0051276 chromosome organization
1.16 1.01e-13 GO:0009987 cellular process
1.36 4.57e-13 GO:0043170 macromolecule metabolic process
1.52 2.00e-12 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.47 2.05e-12 GO:0006325 chromatin organization
1.93 5.47e-12 GO:0007049 cell cycle
2.12 5.14e-11 GO:0022403 cell cycle phase
1.45 8.61e-11 GO:0034641 cellular nitrogen compound metabolic process
1.67 1.05e-10 GO:0006996 organelle organization
1.43 1.76e-10 GO:0006807 nitrogen compound metabolic process
1.50 4.22e-10 GO:0009058 biosynthetic process
1.95 1.60e-09 GO:0022402 cell cycle process
3.46 6.37e-09 GO:0006333 chromatin assembly or disassembly
1.48 8.50e-09 GO:0044249 cellular biosynthetic process
1.45 1.73e-08 GO:0071842 cellular component organization at cellular level
2.09 2.00e-08 GO:0000278 mitotic cell cycle
1.44 2.05e-08 GO:0071841 cellular component organization or biogenesis at cellular level
1.58 4.01e-08 GO:0034645 cellular macromolecule biosynthetic process
3.42 6.51e-08 GO:0006323 DNA packaging
1.57 6.51e-08 GO:0009059 macromolecule biosynthetic process
3.92 6.85e-08 GO:0006334 nucleosome assembly
2.04 1.00e-07 GO:0006259 DNA metabolic process
3.18 1.09e-07 GO:0071103 DNA conformation change
2.21 1.61e-07 GO:0000279 M phase
3.66 2.37e-07 GO:0034728 nucleosome organization
3.72 2.98e-07 GO:0031497 chromatin assembly
3.44 6.82e-07 GO:0071824 protein-DNA complex subunit organization
3.52 6.91e-07 GO:0065004 protein-DNA complex assembly
5.61 7.82e-07 GO:0016126 sterol biosynthetic process
5.90 3.09e-06 GO:0006695 cholesterol biosynthetic process
1.33 4.39e-06 GO:0016043 cellular component organization
1.48 5.13e-06 GO:0010467 gene expression
1.32 7.07e-06 GO:0071840 cellular component organization or biogenesis
1.50 7.57e-06 GO:0016070 RNA metabolic process
1.75 1.17e-05 GO:0033554 cellular response to stress
1.39 1.63e-05 GO:0044267 cellular protein metabolic process
1.86 2.08e-05 GO:0051726 regulation of cell cycle
2.18 2.56e-05 GO:0010564 regulation of cell cycle process
2.14 3.12e-05 GO:0034622 cellular macromolecular complex assembly
2.24 6.78e-05 GO:0000087 M phase of mitotic cell cycle
2.88 8.18e-05 GO:0006310 DNA recombination
2.15 8.31e-05 GO:0006281 DNA repair
1.93 9.19e-05 GO:0034621 cellular macromolecular complex subunit organization
2.04 4.04e-04 GO:0016568 chromatin modification
2.17 4.57e-04 GO:0000280 nuclear division
2.17 4.57e-04 GO:0007067 mitosis
1.27 6.84e-04 GO:0031323 regulation of cellular metabolic process
1.27 6.95e-04 GO:0080090 regulation of primary metabolic process
1.84 8.71e-04 GO:0006974 response to DNA damage stimulus
1.70 1.11e-03 GO:0065003 macromolecular complex assembly
2.10 1.25e-03 GO:0048285 organelle fission
1.61 2.01e-03 GO:0043933 macromolecular complex subunit organization
1.24 2.22e-03 GO:0019222 regulation of metabolic process
1.27 2.29e-03 GO:0060255 regulation of macromolecule metabolic process
2.32 2.70e-03 GO:0006457 protein folding
1.55 3.42e-03 GO:0009892 negative regulation of metabolic process
2.03 4.53e-03 GO:0051325 interphase
2.56 5.22e-03 GO:0051052 regulation of DNA metabolic process
2.02 6.41e-03 GO:0051329 interphase of mitotic cell cycle
1.56 6.46e-03 GO:0031324 negative regulation of cellular metabolic process
1.56 6.53e-03 GO:0010605 negative regulation of macromolecule metabolic process
1.31 8.54e-03 GO:0006950 response to stress
2.21 9.37e-03 GO:0000075 cell cycle checkpoint
2.83 1.00e-02 GO:0006694 steroid biosynthetic process
1.31 1.04e-02 GO:2000112 regulation of cellular macromolecule biosynthetic process
4.78 1.67e-02 GO:0006271 DNA strand elongation involved in DNA replication
1.30 1.68e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.89 1.72e-02 GO:0051301 cell division
2.12 2.35e-02 GO:0071156 regulation of cell cycle arrest
2.69 2.42e-02 GO:0007059 chromosome segregation
1.50 2.64e-02 GO:0032774 RNA biosynthetic process
1.70 2.69e-02 GO:0016071 mRNA metabolic process
1.69 3.16e-02 GO:0044265 cellular macromolecule catabolic process
5.47 3.17e-02 GO:2000104 negative regulation of DNA-dependent DNA replication
1.27 3.38e-02 GO:0051171 regulation of nitrogen compound metabolic process
4.46 3.64e-02 GO:0022616 DNA strand elongation
1.25 3.96e-02 GO:0019538 protein metabolic process
1.57 4.34e-02 GO:0012501 programmed cell death
1.27 4.46e-02 GO:0009889 regulation of biosynthetic process
2.65 4.85e-02 GO:0016125 sterol metabolic process

Gene overrepresentation in compartment category:

enrichment   p-value GO term description
1.34 3.10e-37 GO:0043227 membrane-bounded organelle
1.24 3.45e-37 GO:0044424 intracellular part
1.34 3.85e-37 GO:0043231 intracellular membrane-bounded organelle
1.30 5.33e-37 GO:0043226 organelle
1.30 9.79e-37 GO:0043229 intracellular organelle
1.22 7.68e-36 GO:0005622 intracellular
1.43 8.62e-26 GO:0005634 nucleus
1.42 1.16e-24 GO:0044446 intracellular organelle part
1.42 1.81e-24 GO:0044422 organelle part
1.68 4.43e-18 GO:0070013 intracellular organelle lumen
1.66 2.20e-17 GO:0043233 organelle lumen
2.51 2.79e-17 GO:0005694 chromosome
1.64 6.39e-17 GO:0031974 membrane-enclosed lumen
1.67 8.02e-17 GO:0044428 nuclear part
2.61 5.20e-16 GO:0044427 chromosomal part
3.13 2.24e-13 GO:0000785 chromatin
1.43 7.52e-13 GO:0032991 macromolecular complex
1.21 8.80e-13 GO:0005737 cytoplasm
1.64 1.05e-12 GO:0031981 nuclear lumen
1.76 6.66e-12 GO:0005654 nucleoplasm
1.26 2.98e-10 GO:0044444 cytoplasmic part
1.44 7.37e-10 GO:0043228 non-membrane-bounded organelle
1.44 7.37e-10 GO:0043232 intracellular non-membrane-bounded organelle
4.51 9.63e-08 GO:0000786 nucleosome
1.85 6.16e-07 GO:0044429 mitochondrial part
2.79 1.14e-06 GO:0044454 nuclear chromosome part
1.78 3.05e-06 GO:0031967 organelle envelope
1.34 4.04e-06 GO:0043234 protein complex
3.39 4.09e-06 GO:0032993 protein-DNA complex
2.49 6.91e-06 GO:0000228 nuclear chromosome
1.75 7.56e-06 GO:0031975 envelope
1.51 1.85e-05 GO:0005739 mitochondrion
1.62 1.92e-03 GO:0015630 microtubule cytoskeleton
1.71 2.59e-03 GO:0030529 ribonucleoprotein complex
2.04 2.87e-03 GO:0005759 mitochondrial matrix
1.32 3.73e-03 GO:0005829 cytosol
1.73 4.06e-03 GO:0005740 mitochondrial envelope
2.38 5.19e-03 GO:0000775 chromosome, centromeric region
1.04 5.88e-03 GO:0044464 cell part
1.04 6.05e-03 GO:0005623 cell
1.97 1.33e-02 GO:0005635 nuclear envelope
1.69 1.46e-02 GO:0031966 mitochondrial membrane
6.08 2.15e-02 GO:0042613 MHC class II protein complex
2.53 2.48e-02 GO:0005741 mitochondrial outer membrane
2.26 2.70e-02 GO:0000793 condensed chromosome
1.51 2.71e-02 GO:0044451 nucleoplasm part
2.31 4.86e-02 GO:0031968 organelle outer membrane

Gene overrepresentation in function category:

enrichment   p-value GO term description
1.21 2.12e-09 GO:0005515 protein binding
1.11 3.70e-09 GO:0005488 binding
1.33 6.04e-07 GO:0003676 nucleic acid binding
1.40 3.44e-06 GO:0003677 DNA binding
10.42 1.28e-03 GO:0032404 mismatch repair complex binding
1.28 1.31e-02 GO:0000166 nucleotide binding
3.68 1.65e-02 GO:0042826 histone deacetylase binding
3.04 2.78e-02 GO:0008094 DNA-dependent ATPase activity
6.08 3.29e-02 GO:0030983 mismatched DNA binding
1.15 4.70e-02 GO:0003824 catalytic activity