Motif ID: NFY{A,B,C}.p2

Z-value: 3.263


Transcription factors associated with NFY{A,B,C}.p2:

Gene SymbolEntrez IDGene Name
NFYA 4800 nuclear transcription factor Y, alpha
NFYB 4801 nuclear transcription factor Y, beta
NFYC 4802 nuclear transcription factor Y, gamma

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
NFYAchr6_+_411488690.757.8e-04Click!
NFYCchr1_+_409302330.467.1e-02Click!
NFYBchr12_-_103055924-0.371.5e-01Click!


Activity profile for motif NFY{A,B,C}.p2.

activity profile for motif NFY{A,B,C}.p2


Sorted Z-values histogram for motif NFY{A,B,C}.p2

Sorted Z-values for motif NFY{A,B,C}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NFY{A,B,C}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_23175383 8.648 NM_005794
NM_182908
 DHRS2

dehydrogenase/reductase (SDR family) member 2

chr17_+_73694992 4.663 NM_001010982
NM_001145526
 AFMID

arylformamidase

chr17_-_73694669 4.527 NM_003258
 TK1
thymidine kinase 1, soluble
chr17_+_70256518 3.952


chr8_+_11697588 3.899 NM_004462
 FDFT1
farnesyl-diphosphate farnesyltransferase 1
chr1_+_144149794 3.845 NM_006472
 TXNIP
thioredoxin interacting protein
chr14_+_38714111 3.781 NM_002687
 PNN
pinin, desmosome associated protein
chr20_+_47096280 3.615 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr20_+_47096189 3.578 NM_001316
 CSE1L
CSE1 chromosome segregation 1-like (yeast)
chr17_+_70256341 3.463 NM_004252
 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_+_70256389 3.422 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr2_+_74914742 3.407 HK2
hexokinase 2
chr17_+_70256397 3.392 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_77411733 3.376 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_+_70256370 3.364 SLC9A3R1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr17_-_77411803 3.316 NM_000918
 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr1_+_225194622 3.235 ADCK3
aarF domain containing kinase 3
chr17_-_77411695 3.202 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_-_77411659 3.197 P4HB
prolyl 4-hydroxylase, beta polypeptide
chr17_-_77411707 3.138 P4HB
prolyl 4-hydroxylase, beta polypeptide

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 85 entries
enrichment   p-value GO term description
5.90 3.09e-06 GO:0006695 cholesterol biosynthetic process
5.61 7.82e-07 GO:0016126 sterol biosynthetic process
5.47 3.17e-02 GO:2000104 negative regulation of DNA-dependent DNA replication
4.78 1.67e-02 GO:0006271 DNA strand elongation involved in DNA replication
4.46 3.64e-02 GO:0022616 DNA strand elongation
3.92 6.85e-08 GO:0006334 nucleosome assembly
3.72 2.98e-07 GO:0031497 chromatin assembly
3.66 2.37e-07 GO:0034728 nucleosome organization
3.52 6.91e-07 GO:0065004 protein-DNA complex assembly
3.46 6.37e-09 GO:0006333 chromatin assembly or disassembly
3.44 6.82e-07 GO:0071824 protein-DNA complex subunit organization
3.42 6.51e-08 GO:0006323 DNA packaging
3.18 1.09e-07 GO:0071103 DNA conformation change
2.88 8.18e-05 GO:0006310 DNA recombination
2.83 1.00e-02 GO:0006694 steroid biosynthetic process
2.69 2.42e-02 GO:0007059 chromosome segregation
2.65 4.85e-02 GO:0016125 sterol metabolic process
2.56 5.22e-03 GO:0051052 regulation of DNA metabolic process
2.47 2.05e-12 GO:0006325 chromatin organization
2.33 7.32e-14 GO:0051276 chromosome organization

Gene overrepresentation in compartment category:

Showing 1 to 20 of 47 entries
enrichment   p-value GO term description
6.08 2.15e-02 GO:0042613 MHC class II protein complex
4.51 9.63e-08 GO:0000786 nucleosome
3.39 4.09e-06 GO:0032993 protein-DNA complex
3.13 2.24e-13 GO:0000785 chromatin
2.79 1.14e-06 GO:0044454 nuclear chromosome part
2.61 5.20e-16 GO:0044427 chromosomal part
2.53 2.48e-02 GO:0005741 mitochondrial outer membrane
2.51 2.79e-17 GO:0005694 chromosome
2.49 6.91e-06 GO:0000228 nuclear chromosome
2.38 5.19e-03 GO:0000775 chromosome, centromeric region
2.31 4.86e-02 GO:0031968 organelle outer membrane
2.26 2.70e-02 GO:0000793 condensed chromosome
2.04 2.87e-03 GO:0005759 mitochondrial matrix
1.97 1.33e-02 GO:0005635 nuclear envelope
1.85 6.16e-07 GO:0044429 mitochondrial part
1.78 3.05e-06 GO:0031967 organelle envelope
1.76 6.66e-12 GO:0005654 nucleoplasm
1.75 7.56e-06 GO:0031975 envelope
1.73 4.06e-03 GO:0005740 mitochondrial envelope
1.71 2.59e-03 GO:0030529 ribonucleoprotein complex

Gene overrepresentation in function category:

Showing 1 to 10 of 10 entries
enrichment   p-value GO term description
10.42 1.28e-03 GO:0032404 mismatch repair complex binding
6.08 3.29e-02 GO:0030983 mismatched DNA binding
3.68 1.65e-02 GO:0042826 histone deacetylase binding
3.04 2.78e-02 GO:0008094 DNA-dependent ATPase activity
1.40 3.44e-06 GO:0003677 DNA binding
1.33 6.04e-07 GO:0003676 nucleic acid binding
1.28 1.31e-02 GO:0000166 nucleotide binding
1.21 2.12e-09 GO:0005515 protein binding
1.15 4.70e-02 GO:0003824 catalytic activity
1.11 3.70e-09 GO:0005488 binding